Searchable abstracts of presentations at key conferences on calcified tissues

ba0002p134 | (1) | ICCBH2013

Cessation of ambulation results in a dramatic loss of trabecular bone density in boys with Duchenne muscular dystrophy

Crabtree Nicola , Bebbington Natalie , Roper Helen , McMurchie Heather , Shaw Nicholas

Steroids are currently used to improve muscle strength and prolong ambulation in boys with Duchenne muscular dystrophy (DMD) although the effect on bone health is still unclear. The aim of this study was to compare bone strength in healthy children and boys with DMD and investigate the interaction between diminished muscle function, loss of ambulation and high dose oral steroids.Fifty children were studied, 14 healthy boys (HB), 13 boys with DMD who rema...